BDBM50498114 CHEMBL3403036

SMILES CCn1cc(NC(=O)c2ccc(Cn3nc(C)cc3C)o2)c(n1)C(=O)NC

InChI Key InChIKey=VXPYRJPHECESIV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498114   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Kyoto University

Curated by ChEMBL

LigandBDBM50498114(CHEMBL3403036)Copy SMILESCopy InChI

Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of HIF1 in human HT1080 cells transfected with 5xHRE/pGL3/VEGF/E1b reporter plasmid pre-incubated for 1 hr followed by incubation under hy...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/3/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL