BDBM50497951 CHEMBL3323403

SMILES COc1ccc(Cl)cc1Nc1nc-2c(CCCc3nc(NC(=O)c4ccno4)sc-23)s1

InChI Key InChIKey=NZECEECRQJTTNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497951   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50497951(CHEMBL3323403)
Affinity DataIC50: 4.80E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed