BDBM50497801 CHEMBL3330119

SMILES COc1ccc(CNc2nccc(n2)-c2cc(C(N)=O)c([nH]2)-c2cc(Cl)ccc2C)cc1

InChI Key InChIKey=MFHGBONQYSNHIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497801   

TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497801(CHEMBL3330119)
Affinity DataIC50: 394nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed