BDBM50497437 CHEMBL3343701

SMILES Fc1c(F)c(F)c2n(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)ncc2c1F

InChI Key InChIKey=YEUDGKFAVCEXHA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50497437   

TargetNischarin(Rat)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497437(CHEMBL3343701)
Affinity DataIC50: 5.83E+3nMAssay Description:Displacement of [3H]2BF1 from imidazoline I1 receptor in Sprague-Dawley rat kidney membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497437(CHEMBL3343701)
Affinity DataKi:  3.72E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497437(CHEMBL3343701)
Affinity DataKi:  1.98E+4nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed