BDBM50496947 CHEMBL3236469

SMILES CCCS(=O)(=O)Nc1ccc(F)c(N(CC)c2ccc3ncn(C)c(=O)c3c2)c1Cl

InChI Key InChIKey=OGYQETQKMSCPAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496947   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50496947(CHEMBL3236469)
Affinity DataIC50: 603nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50496947(CHEMBL3236469)
Affinity DataIC50: 30nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed