BDBM50496844 CHEMBL3218637

SMILES [H][C@@]12CCCCN1C(=O)C(=O)C(C)(C)COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccc3ccccc3c1)NC(=O)[C@H](CCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)C[C@@H](CCc1ccccc1)NC2=O

InChI Key InChIKey=KGLOEUYWNJLLKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496844   

TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50496844(CHEMBL3218637)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant HA-tagged K-Ras G12V mutant (unknown origin) assessed as disruption of interaction with GST-tagged Raf-RBD after overnight ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed