BDBM50496834 CHEMBL2171679

SMILES COc1ccc(cc1)S(=O)(=O)N1Cc2cc(ccc2N(Cc2cncn2C)C[C@H]1Cc1ccc(OC(=O)NCc2ccccc2)cc1)-c1ccc(o1)C#N

InChI Key InChIKey=UNJUKEICOWKRIH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496834   

TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
University of Minnesota

Curated by ChEMBL

LigandBDBM50496834(CHEMBL2171679)Copy SMILESCopy InChI

Affinity DataIC50: 9.95E+4nMAssay Description:Inhibition of human GGTase1 in human Burkitt lymphoma (Daudi) cell supernatant using [3H]geranylgeranylMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
University of Minnesota

Curated by ChEMBL

LigandBDBM50496834(CHEMBL2171679)Copy SMILESCopy InChI

Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human recombinant FTase using [3H]farnesyldiphosphateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL