BDBM50496577 CHEMBL3134008

SMILES CC(C)CN(C(=O)Nc1ccc(CCC(O)=O)cc1Cc1ccccc1)C(=O)c1ccc(OCC(O)=O)c(Cc2ccccc2)c1

InChI Key InChIKey=LOXAFWABBGFKKO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50496577   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50496577(CHEMBL3134008)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase by steady state kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50496577(CHEMBL3134008)
Affinity DataIC50: 5.70E+5nMAssay Description:Inhibition of thymidylate synthase activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase by steady state kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50496577(CHEMBL3134008)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed