BDBM50496569 CHEMBL3133862

SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3cc(OCCOCCOCCF)ccc3[nH]2)CC1

InChI Key InChIKey=PWXSXDYNNANOIK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496569   

TargetD(3) dopamine receptor(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496569(CHEMBL3133862)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]ABN from human D3 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496569(CHEMBL3133862)
Affinity DataKi:  42nMAssay Description:Displacement of [125I]ABN from human D2 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496569(CHEMBL3133862)
Affinity DataKi:  565nMAssay Description:Displacement of [125I]ABN from human D4 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496569(CHEMBL3133862)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in guinea pig brain membrane after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed