BDBM50496424 CHEMBL3127573

SMILES Fc1ccc(cc1)-c1cnnn1-c1ccc2OS(=O)(=O)C=Cc2c1

InChI Key InChIKey=BEYJSXSPCJPMOA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50496424   

TargetCarbonic anhydrase 12(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50496424(CHEMBL3127573)
Affinity DataKi:  5.40nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50496424(CHEMBL3127573)
Affinity DataKi:  6.90nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50496424(CHEMBL3127573)
Affinity DataKi:  7.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12-mediated CO2 hydration after 6 hrs by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50496424(CHEMBL3127573)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9-mediated CO2 hydration after 6 hrs by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50496424(CHEMBL3127573)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1-mediated CO2 hydration after 6 hrs by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50496424(CHEMBL3127573)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2-mediated CO2 hydration after 6 hrs by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed