BDBM50496346 CHEMBL3126196

SMILES NC(C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1

InChI Key InChIKey=AUWUGRCKTQSGJY-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496346   

TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataIC50: 67nMAssay Description:Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataIC50: 185nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to biotinylated Menin (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataKi:  58nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed