BDBM50495594 CHEMBL3114095

SMILES O=S1(=O)Oc2ccc(cc2C=C1)-c1nnnn1-c1ccccc1

InChI Key InChIKey=JTEXTXISPSGJGM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50495594   

TargetCarbonic anhydrase 12(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50495594(CHEMBL3114095)
Affinity DataKi:  5.40nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50495594(CHEMBL3114095)
Affinity DataKi:  6.90nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50495594(CHEMBL3114095)
Affinity DataKi:  7.10nMAssay Description:Inhibition of human recombinant transmembrane carbonic anhydrase 12 after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50495594(CHEMBL3114095)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human recombinant transmembrane carbonic anhydrase 9 after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50495594(CHEMBL3114095)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50495594(CHEMBL3114095)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 after 6 hrs by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed