BDBM50494811 CHEMBL3094350

SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(C)(CC1)C(O)=O

InChI Key InChIKey=VWGVZRSKDSKOCX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50494811   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandPNGBDBM50494811(CHEMBL3094350)
Affinity DataIC50: 15.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandPNGBDBM50494811(CHEMBL3094350)
Affinity DataIC50: 15.5nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50494811(CHEMBL3094350)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Escherichia coli DNA gyrase (A2B2 tetramer) incubated for 60 mins in presence of ATP by malachite green reagent based spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed