BDBM50494716 CHEMBL3093986

SMILES CCCCCCCN(CC)C\C=C\Cc1ccc(Cl)cc1

InChI Key InChIKey=RDBQYAIRRCCEQW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50494716   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50494716(CHEMBL3093986)
Affinity DataIC50: 5nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50494716(CHEMBL3093986)
Affinity DataIC50: 49nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50494716(CHEMBL3093986)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed