BDBM50494414 CHEMBL3086768

SMILES ONC(=O)CCCC(=O)NCCc1ccccc1

InChI Key InChIKey=MNMBNWINDLRVJD-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50494414   

TargetHistone deacetylase 6(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 386nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC4 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant HDAC2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus expression system using fluorogenic substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged/N-terminal GST-tagged human HDAC4 (627 to 1084 residues) expressed in baculovirus expression system u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal FLAG-tagged/C-terminal His-tagged human HDAC1 using fluorogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using fluorogenic substrate by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human HDAC2 expressed in baculovirus expression system using fluorogenic peptide RHKK(Ac) as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC2 expressed in baculovirus expression system using fluorogenic substrate by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus expression system using fluorogenic substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculovirus expression system using fluorogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC3/GST-tagged human Ncor2 (395 to 489 residues) expressed in baculovirus express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC5 catalytic domain (656 to 1122 residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus expression system using fluorogenic subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494414(CHEMBL3086768)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic substrate by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed