BDBM50494194 CHEMBL3086101

SMILES C[C@](O)(C1CCN(CC1)c1nccnc1Oc1ccc(cc1)C(=O)c1nc2ccccc2[nH]1)C(F)(F)F

InChI Key InChIKey=ADMPHCQUPDYFKW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494194   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

Curated by ChEMBL

LigandBDBM50494194(CHEMBL3086101)Copy SMILESCopy InChI

Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by IMAP TR-FR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
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