BDBM50493582 CHEMBL2435818

SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NCCc1ccccc1

InChI Key InChIKey=RLIIGJWNLLPVGV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50493582   

TargetType-1 angiotensin II receptor(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50493582(CHEMBL2435818)
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from human AT1 receptor expressed in CHO-K1 cell membranes after 180 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50493582(CHEMBL2435818)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT1 receptor (unknown origin) after 180 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50493582(CHEMBL2435818)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT2 receptor (unknown origin) after 180 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed