BDBM50493278 CHEMBL2425947

SMILES COc1ccc(cc1)S(=O)(=O)N(CCn1cc(CCCF)nn1)[C@H](C(C)C)C(=O)NO

InChI Key InChIKey=MFOJAATVHNHXKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50493278   

TargetCollagenase 3(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493278(CHEMBL2425947)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of MMP-13 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493278(CHEMBL2425947)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP-8 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493278(CHEMBL2425947)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of MMP-9 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50493278(CHEMBL2425947)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of MMP-2 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed