BDBM50493044 CHEMBL2418741

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5([H])C[C@@H](O)[C@@H]2O)ccc3OC

InChI Key

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50493044   

TargetKappa-type opioid receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50493044(CHEMBL2418741)
Affinity DataEC50:  1.26E+5nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50493044(CHEMBL2418741)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50493044(CHEMBL2418741)
Affinity DataEC50:  1.60E+4nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50493044(CHEMBL2418741)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50493044(CHEMBL2418741)
Affinity DataEC50:  1.59E+5nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed