BDBM50492823 CHEMBL2413289

SMILES Cc1ccc(OCCN(CCc2ccc3OCOc3c2)Cc2ccc(\C=C\C(=O)NO)o2)cc1

InChI Key InChIKey=BOEDISARXAMAME-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50492823   

TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492823(CHEMBL2413289)
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of human recombinant HDAC6 using p53 residues 379-382 (RHKKAc) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492823(CHEMBL2413289)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of human recombinant HDAC1 using p53 residues 379-382 (RHKKAc) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492823(CHEMBL2413289)
Affinity DataIC50: 5.25E+4nMAssay Description:Inhibition of human recombinant HDAC4 using p53 residues 379-382 (RHKKAc) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492823(CHEMBL2413289)
Affinity DataIC50: 840nMAssay Description:Inhibition of HDAC in human HeLa cell extract using Fluor deLys as substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed