BDBM50492802 CHEMBL2414356

SMILES Clc1ccc(cc1)-n1cc(CCCN2CCN(CC2)c2ccccc2)cn1

InChI Key InChIKey=HIFJFKUAMBPYFD-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50492802   

Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  600nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  680nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  700nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed