BDBM50492759 CHEMBL2413569

SMILES O=C1c2ccccc2C(=O)c2cc(Cn3cc(COCc4cn(Cc5ccc6C(=O)c7ccccc7C(=O)c6c5)nn4)nn3)ccc12

InChI Key InChIKey=YTNPZRSFESTBAF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492759   

TargetHeat shock protein HSP 90-beta(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50492759(CHEMBL2413569)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to human Hsp90 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50492759(CHEMBL2413569)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human Hsp90 ATPase activity assessed as inhibition of ATP hydrolysis after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed