BDBM50492418 CHEMBL2401849

SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)Cc2ccc(NC(=O)CCCCCCC(=O)NO)cc2)cc1)c1ccccc1

InChI Key InChIKey=QMIYTBVVEXLKCW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50492418   

TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)
Affinity DataIC50: 221nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)
Affinity DataIC50: 127nMAssay Description:Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)
Affinity DataIC50: 221nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed