BDBM50492024 2''-Methoxy Liquiritigenin::2''-Methoxyisoliquiritigenin::2''-O-Methylisoliquiritigenin::3''-Deoxy-Sappanchalcone::3-Deoxysappanchalcone::CHEBI:519567::CHEMBL253777

SMILES COc1cc(O)ccc1C(=O)\C=C\c1ccc(O)cc1

InChI Key InChIKey=PACBGANPVNHGNP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50492024   

TargetNeuraminidase(Influenza A virus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50492024(CHEBI:519567 | 2''-Methoxy Liquiritigenin | 2''-Me...)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of Influenza A virus H1N1 neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50492024(CHEBI:519567 | 2''-Methoxy Liquiritigenin | 2''-Me...)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of human erythrocytes mu-calpain using Pep2 as substrate incubated for 30 mins under shaking condition in presence of CaCl2 by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Ain-Shams University

Curated by ChEMBL
LigandPNGBDBM50492024(CHEBI:519567 | 2''-Methoxy Liquiritigenin | 2''-Me...)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50492024(CHEBI:519567 | 2''-Methoxy Liquiritigenin | 2''-Me...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of human MAO-A using kynuramine as substrate incubated for 20 mins by fluorescence based assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50492024(CHEBI:519567 | 2''-Methoxy Liquiritigenin | 2''-Me...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human MAO-B using kynuramine as substrate incubated for 20 mins by fluorescence based assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed