BDBM50491910 CHEMBL2385449

SMILES OC(=O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(NC(=O)c2cc(F)ccn2)cc1

InChI Key InChIKey=CJDLHVDTFICCKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491910   

TargetMatrix metalloproteinase-9(Human)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50491910(CHEMBL2385449)
Affinity DataIC50: 38nMAssay Description:Inhibition of human full length MMP9 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50491910(CHEMBL2385449)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed