BDBM50491907 CHEMBL2385441

SMILES OC(=O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=QZZBJIXIULKRDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50491907   

Target72 kDa type IV collagenase(Human)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50491907(CHEMBL2385441)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50491907(CHEMBL2385441)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50491907(CHEMBL2385441)
Affinity DataIC50: 7nMAssay Description:Inhibition of human full length MMP9 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed