BDBM50491736 CHEMBL2385759

SMILES CC(C)(C)CNC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccccc2)cc1

InChI Key InChIKey=JETOXSSXLNZTNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491736   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50491736(CHEMBL2385759)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant PDE4B (152 to 564 amino acids) using cAMP as substrate after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed