BDBM50491706 CHEMBL2387673

SMILES OC(=O)C1CCCN(CCO\C=C/c2cc(F)ccc2Cc2ccc(F)cc2)C1

InChI Key InChIKey=JRTSDOUKJZFNHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50491706   

TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50491706(CHEMBL2387673)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50491706(CHEMBL2387673)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50491706(CHEMBL2387673)
Affinity DataIC50: 9.12E+4nMAssay Description:Inhibition of mouse GAT2 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed