BDBM50491621 CHEMBL2386140

SMILES CC(C)(C)c1ccc(cc1)-c1ccc(F)cn1

InChI Key InChIKey=HLEIOPTVJNIOBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491621   

TargetCytochrome P450 3A4/3A5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491621(CHEMBL2386140)
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed