BDBM50491558 CHEMBL2046885

SMILES CCN(CC)CCOc1cccc2oc3c4NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]5(C)Oc6c(C5=O)c(c3nc12)c(c(O)c6C)c4=O

InChI Key InChIKey=NCYSEZCFZIFVEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50491558   

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50491558(CHEMBL2046885)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of rifamycin-resistant Escherichia coli RNA polymerase S531L mutant after 10 mins by rolling circle transcription assay in presence of DNA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50491558(CHEMBL2046885)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of rifamycin-resistant Escherichia coli RNA polymerase D516V mutant after 10 mins by rolling circle transcription assay in presence of DNA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50491558(CHEMBL2046885)
Affinity DataIC50: 1.15E+6nMAssay Description:Inhibition of rifamycin-resistant Escherichia coli RNA polymerase H526Y mutant after 10 mins by rolling circle transcription assay in presence of DNA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed