BDBM50491545 CHEMBL2380874

SMILES Cc1onc(-c2ccco2)c1-c1ccccc1

InChI Key InChIKey=KXQLLEQKHARGDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491545   

TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491545(CHEMBL2380874)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491545(CHEMBL2380874)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed