BDBM50490943 CHEMBL2376364

SMILES CCN(C(C)C)C(=O)C1CCN(CC1)C(=O)Nc1cccc(Cn2nc(Nc3ccccc3C)ccc2=O)c1

InChI Key InChIKey=TTWFRFONBLFDLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50490943   

TargetAcetylcholinesterase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50490943(CHEMBL2376364)
Affinity DataIC50: 28nMAssay Description:Inhibition of AChE in rat cerebral cortex homogenates using acetylthiocholine iodide as substrate after 8 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50490943(CHEMBL2376364)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of rat serum BuChE using S-butyrylthiocholine iodide as substrate after 8 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed