BDBM50490918 CHEMBL2347710

SMILES CCNC(=O)Nc1nc2ccc(cc2s1)-c1ccccc1OC

InChI Key InChIKey=LGPZTQXZPZVKSU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50490918   

TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490918(CHEMBL2347710)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490918(CHEMBL2347710)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of wild type Abl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490918(CHEMBL2347710)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50490918(CHEMBL2347710)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of wild type Abl in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50490918(CHEMBL2347710)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of Abl T315I mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed