BDBM50490888 CHEMBL2347725

SMILES COc1ccccc1-c1ccc2nc(NC(=O)NCCN3CCN(C)CC3)sc2c1

InChI Key InChIKey=AIZRLMRCMYABCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50490888   

TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50: 46nMAssay Description:Inhibition of wild type Abl in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50: 78nMAssay Description:Inhibition of Abl T315I mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed