BDBM50490585 CHEMBL602560

SMILES [H][C@]1(CCCN1C(C)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@H]1C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@H]1C(N)=O

InChI Key InChIKey=SOJGGYHOKDQKJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50490585   

TargetPresenilin-1(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490585(CHEMBL602560)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490585(CHEMBL602560)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed