BDBM50490553 CHEMBL1232569

SMILES c1c(nc[nH]1)Br

InChI Key InChIKey=FHZALEJIENDROK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50490553   

TargetEndolysin(Enterobacteria phage T4)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50490553(CHEMBL1232569)
Affinity DataKd:  3.17E+5nMAssay Description:Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102H double mutant expressed in Escherichia coli BL21(DE3) by isothermal titration calorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50490553(CHEMBL1232569)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed