BDBM50489435 CHEMBL2326381

SMILES Cc1c(OCCC2CCCCN2)ccc2cc(NC(=O)Nc3ccc(Cl)cc3)c(=O)oc12

InChI Key InChIKey=ZXALUOVHERVPSO-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50489435   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50489435(CHEMBL2326381)
Affinity DataIC50: 210nMAssay Description:Inhibition of Hsp90 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50489435(CHEMBL2326381)
Affinity DataKd:  1.91E+5nMAssay Description:Binding affinity to recombinant HSP90alpha (unknown origin) assessed as dissociation constant incubated for 30 mins by intrinsic fluorescence based s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50489435(CHEMBL2326381)
Affinity DataKd:  7.26E+5nMAssay Description:Binding affinity to recombinant HSP90beta (unknown origin) assessed as dissociation constant incubated for 30 mins by intrinsic fluorescence based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed