BDBM50489368 CHEMBL2315846

SMILES CC(C)C1=C(SC2=N[C@](C)([C@H](N12)c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1CC[C@H]1C(=O)N(C)C

InChI Key InChIKey=SJOTXTWUPGBVMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50489368   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50489368(CHEMBL2315846)
Affinity DataIC50: 140nMAssay Description:Inhibition of human His-tagged p53 (1 to 132 amino acid residues)/GST-tagged MDM2 L33E mutant (25 to 108 amino acid residues) interaction by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed