BDBM50488819 CHEMBL2295949

SMILES CC(C)C[C@@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=HGRMYMRCAGWXEQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50488819   

LigandPNGBDBM50488819(CHEMBL2295949)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant CDK2/cyclin A using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50488819(CHEMBL2295949)
Affinity DataIC50: 500nMAssay Description:Inhibition of Homo sapiens (human) recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ and [gamma33P]ATP as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50488819(CHEMBL2295949)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50488819(CHEMBL2295949)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Sus scrofa (pig) casein kinase 1delta/epsilon isolated from brain using RRKHAAIGpSAYSITA and [gamma33P]ATP as substrate after 30 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50488819(CHEMBL2295949)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Sus scrofa (pig) glycogen synthase kinase 3alpha/beta isolated from brain using YRRAAVPPSPSLSRHSSPHQpSEDEEE and [gamma33P]ATP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article