BDBM50487731 CHEMBL2262117

SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1cccc(Cl)c1

InChI Key InChIKey=ZIQVOGGFHZSARK-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50487731   

TargetTubulin alpha chain(Sheep)TBA
LigandPNGBDBM50487731(CHEMBL2262117)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Sheep)TBA
LigandPNGBDBM50487731(CHEMBL2262117)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 30 min by CD spectra analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTubulin alpha chain(Sheep)TBA
LigandPNGBDBM50487731(CHEMBL2262117)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to Ovis aries (sheep) brain tubulin assessed as intrinsic tryptophan fluorescence after 30 min by fluorescence spectroscopic analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article