BDBM50487418 CHEMBL2261693

SMILES CCOC(=O)C1=C(C)N=C(NC1c1ccccc1)SCC(=O)c1ccc(Cl)c(c1)[N+]([O-])=O

InChI Key InChIKey=VGTPYWFPZMWGMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50487418   

TargetDihydrofolate reductase(Human)TBA
LigandPNGBDBM50487418(CHEMBL2261693)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Homo sapiens (human) dihydrofolate reductase using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50487418(CHEMBL2261693)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Cryptosporidium parvum recombinant DHFR using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article