BDBM50487416 CHEMBL2261696

SMILES CCOC(=O)C(\SC1=NC(C(C(=O)OCC)=C(C)N1)c1ccccc1)=C\c1ccc(OC)cc1

InChI Key InChIKey=KZCLZTHWXHXZDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50487416   

TargetDihydrofolate reductase(Human)TBA
LigandPNGBDBM50487416(CHEMBL2261696)
Affinity DataIC50: 10nMAssay Description:Inhibition of Homo sapiens (human) dihydrofolate reductase using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50487416(CHEMBL2261696)
Affinity DataIC50: 38nMAssay Description:Inhibition of Cryptosporidium parvum recombinant DHFR using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article