BDBM50487065 2,3-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID

SMILES OP(O)(=O)C(Nc1cccc(Cl)c1Cl)P(O)(O)=O

InChI Key InChIKey=MHZIAHXWTPYINE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50487065   

TargetGlutamine synthetase, chloroplastic(Maize)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487065(2,3-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetGlutamine synthetase, chloroplastic(Maize)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487065(2,3-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487065(2,3-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487065(2,3-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed