BDBM50486850 CHEMBL58557

SMILES COc1ccc(\C=C\C(=O)c2ccc(cc2)C(F)(F)F)c(OC)c1

InChI Key InChIKey=SSFSCIRMLOMJJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50486850   

TargetTrophozoite cysteine proteinase(malaria parasite P. falciparum)TBA
LigandPNGBDBM50486850(CHEMBL58557)
Affinity DataIC50: 750nMAssay Description:Inhibition of Plasmodium falciparum W2 cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTrophozoite cysteine proteinase(malaria parasite P. falciparum)TBA
LigandPNGBDBM50486850(CHEMBL58557)
Affinity DataIC50: 750nMAssay Description:Inhibition of Plasmodium falciparum W2 cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetCytochrome P450 1B1(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50486850(CHEMBL58557)
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed