BDBM50486048 CHEMBL2204513

SMILES OCc1ccc(cc1)C(=O)NC1CC2CCC(C1)N2c1ccc(cn1)C(=O)NCc1ccccc1

InChI Key InChIKey=WZLRGNSIRYXMJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50486048   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486048(CHEMBL2204513)
Affinity DataIC50: 322nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486048(CHEMBL2204513)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Hsp90 in human A549 cells assessed as Raf1 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed