BDBM50486040 CHEMBL2204523

SMILES CCNC(=O)c1ccc(nc1)N1C2CCC1CC(C2)NC(=O)c1ccc(C(N)=O)c(NCC2CC2)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50486040   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486040(CHEMBL2204523)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of Hsp90 in human NCI-N87 cells assessed as Her2 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486040(CHEMBL2204523)
Affinity DataIC50: 104nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed