BDBM50486039 CHEMBL2204522

SMILES NC(=O)c1ccc(cc1NCC1CC1)C(=O)NC1CC2CCC(C1)N2c1ccc(cn1)C(=O)NC1CCCC1

InChI Key InChIKey=LIIPKRTYBSDBDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50486039   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486039(CHEMBL2204522)
Affinity DataIC50: 351nMAssay Description:Inhibition of Hsp90 in human NCI-N87 cells assessed as Her2 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486039(CHEMBL2204522)
Affinity DataIC50: 89nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed