BDBM50485994 CHEMBL2203385

SMILES Cn1ccc2cc(cnc12)-c1nc2ccc(F)nc2o1

InChI Key InChIKey=WYQHKOHCTMNFAU-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485994   

TargetAmyloid-beta precursor protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50485994(CHEMBL2203385)
Affinity DataIC50: 11nMAssay Description:Binding affinity to human amyloid beta plaqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50485994(CHEMBL2203385)
Affinity DataKd:  9.60nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed