BDBM50485936 CHEMBL2179463

SMILES CCc1cc[n+](cc1)-c1cc[n+](Cc2cc(C[n+]3ccc(cc3)-c3cc[n+](CC)cc3)cc(C[n+]3ccc(cc3)-c3cc[n+](Cc4cc(C[n+]5ccc(cc5)-c5cc[n+](Cc6cc(C[n+]7ccc(cc7)-c7cc[n+](CC)cc7)cc(C[n+]7ccc(cc7)-c7cc[n+](CC)cc7)c6)cc5)cc(c4)-[n+]4ccc(cc4)-c4cc[n+](cc4)-c4cc(C[n+]5ccc(cc5)-c5cc[n+](Cc6cc(C[n+]7ccc(cc7)-c7cc[n+](CC)cc7)cc(C[n+]7ccc(cc7)-c7cc[n+](CC)cc7)c6)cc5)cc(C[n+]5ccc(cc5)-c5cc[n+](Cc6cc(C[n+]7ccc(cc7)-c7cc[n+](CC)cc7)cc(C[n+]7ccc(cc7)-c7cc[n+](CC)cc7)c6)cc5)c4)cc3)c2)cc1

InChI Key InChIKey=PVRMMLZVQAHIEW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50485936   

TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485936(CHEMBL2179463)
Affinity DataIC50: 208nMAssay Description:Inhibition of anti-CXCR4 mAbs clone 173 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485936(CHEMBL2179463)
Affinity DataIC50: 536nMAssay Description:Antagonist activity against CXCR4 expressed in U87.CD.CXCR4 cells assessed as inhibition of CXCL12-induced calcium signaling incubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485936(CHEMBL2179463)
Affinity DataIC50: 342nMAssay Description:Inhibition of anti-CXCR4 mAbs clone 12G5 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485936(CHEMBL2179463)
Affinity DataIC50: 283nMAssay Description:Inhibition of CXCL-12'AF647 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485936(CHEMBL2179463)
Affinity DataIC50: 447nMAssay Description:Inhibition of anti-CXCR4 mAbs clone 1D9 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 5(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485936(CHEMBL2179463)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity against CXCR5 expressed in U87.CD.CXCR5 cells assessed as inhibition of CCL3L1-induced calcium signaling incubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed