BDBM50485933 CHEMBL2179460

SMILES Cc1cn(CCC[n+]2ccc(cc2)-c2cc[n+](Cc3cc(C[n+]4ccc(cc4)-c4cc[n+](CCCn5cc(C)c(=O)[nH]c5=O)cc4)cc(c3)-[n+]3ccc(cc3)-c3cc[n+](cc3)-c3cc(C[n+]4ccc(cc4)-c4cc[n+](CCCn5cc(C)c(=O)[nH]c5=O)cc4)cc(C[n+]4ccc(cc4)-c4cc[n+](CCCn5cc(C)c(=O)[nH]c5=O)cc4)c3)cc2)c(=O)[nH]c1=O

InChI Key InChIKey=GTHIYFVBTPTHGQ-UHFFFAOYSA-R

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50485933   

TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485933(CHEMBL2179460)
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of anti-CXCR4 mAbs clone 1D9 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485933(CHEMBL2179460)
Affinity DataIC50: 676nMAssay Description:Inhibition of anti-CXCR4 mAbs clone 173 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485933(CHEMBL2179460)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of CXCL-12'AF647 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485933(CHEMBL2179460)
Affinity DataIC50: 740nMAssay Description:Inhibition of anti-CXCR4 mAbs clone 12G5 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 5(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485933(CHEMBL2179460)
Affinity DataIC50: 3.22E+4nMAssay Description:Antagonist activity against CXCR5 expressed in U87.CD.CXCR5 cells assessed as inhibition of CCL3L1-induced calcium signaling incubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of Osnabr£Ck

Curated by ChEMBL
LigandPNGBDBM50485933(CHEMBL2179460)
Affinity DataIC50: 2.09E+4nMAssay Description:Antagonist activity against CXCR4 expressed in U87.CD.CXCR4 cells assessed as inhibition of CXCL12-induced calcium signaling incubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed